Poengki Dwi Poerwantoro
Head of Burn Unit Pertamina Central Hospital
Title: Double Benefits of Adipose Derived Stem Cell for Aesthetics Procedure
Biography
Biography: Poengki Dwi Poerwantoro
Abstract
Adipose-Derived Stem Cells (ADSC) is considered a source of Mesenchymal Stem Cells (MSC), which can be harvested in large quantities with simple and low morbidity procedure through liposuction. ADSC then will be isolated and cultured to produce a large amount of stem cell. This review explores the double benefit of ADSC usage in regenerative medicine, aesthetic procedures, and antiageing therapy. ADSC can be a very good source for replacement of soft tissues such as breast augmentation, soft tissue filler to fill defect or aging crease in the face, augmentation during face-lift and facial contouring surgeries. ADSC counteract the appearance of skin aging not only via direct cell-to-cell interactions but also through paracrine effects of the various secreted growth factors and cytokines, protecting skin from damage due to oxidative stress. ADSC could provide millions to billions of stem cells and could safely and effectively be used in either an autologous or allogeneic host. The nature of ADSC is immuno-compatible, and there is no ethical concern for their use thus no complication or adverse side effects were noticed. ADSC holds the potential of self-renewal and differentiation into cells with ectodermal, mesodermal and endodermal characteristics and could be produced according to current Good Manufacturing Practice (GMP) guidelines. These ADSC characteristic superiority has given double benefits of ADSC for aesthetic and regenerative medicinal purposes.